Gene Information
Gene NameSCYL2
OrganismHomo sapiens (Human)
Gene Length929
Protein NamesSCY1-like protein 2 (Coated vesicle-associated kinase of 104 kDa)
Target NameNA
Target TypeNA
Gene Age1714 ( ENSG00000136021 )
Evolutionary StageEukaryota
AlphaFoldDBQ6P3W7
Gene CardSCYL2
Uniprot IDQ6P3W7
PfamPF00069
In ASDno
Allosteric Predictionno (-0.741241725)
Ortholog in AnimalsAlpaca_ SCYL2 ( ortholog_one2one )
Dog_ SCYL2 ( ortholog_one2one )
GuineaPig_ SCYL2 ( ortholog_one2one )
Macaque_ SCYL2 ( ortholog_one2one )
Mouse_ Scyl2 ( ortholog_one2one )
Pig_ SCYL2 ( ortholog_one2one )
Rat_ Scyl2 ( ortholog_one2one )
Rabbit_ SCYL2 ( ortholog_one2one )
OhnologsNA
ParalogsSCYL1, SCYL3
TissueNA
Tissue SpecificityNA
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs33968174  rs763873645 
Subcellular location [CC]Cytoplasmic vesicle, clathrin-coated vesicle {ECO:0000269|PubMed:15809293, ECO:0000269|PubMed:16914521}. Golgi apparatus, trans-Golgi network membrane {ECO:0000269|PubMed:16914521}. Endosome membrane {ECO:0000269|PubMed:16914521}. Note=Colocalizes to the trans-Golgi network (TGN) and to endosomal membranes with clathrin, transferrin and plasma membrane adapter AP1 and AP3 complexes. {ECO:0000269|PubMed:16914521}.
Mouse PG classificationNA
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