| Gene Information | |
|---|---|
| Gene Name | FMNL3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 1028 |
| Protein Names | Formin-like protein 3 (Formin homology 2 domain-containing protein 3) (WW domain-binding protein 3) (WBP-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000161791 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8IVF7 |
| Gene Card | FMNL3 |
| Uniprot ID | Q8IVF7 |
| Pfam | PF06367; PF06371; PF02181 |
| In ASD | no |
| Allosteric Prediction | no (-1.181447189) |
| Ortholog in Animals | Alpaca_ FMNL3 ( ortholog_one2one ) Dog_ FMNL3 ( ortholog_one2one ) GuineaPig_ FMNL3 ( ortholog_one2one ) Macaque_ FMNL3 ( ortholog_one2one ) Mouse_ Fmnl3 ( ortholog_one2one ) Pig_ FMNL3 ( ortholog_one2one ) Rat_ Fmnl3 ( ortholog_one2one ) Rabbit_ FMNL3 ( ortholog_one2one ) |
| Ohnologs | FMNL1, FMNL2 |
| Paralogs | FHOD3, FHOD1, FHDC1, GRID2IP, FAM47B, DAAM2, FNBP4, SHTN1, FAM47C, FAM47A, FMNL1, DAAM1, DIAPH3, DIAPH2, FMN2, FMNL2, INF2, DIAPH1 |
| Tissue | NA |
| Tissue Specificity | Expressed in endothelial cells. {ECO:0000269|PubMed:22275430}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:21834987}. Cell membrane {ECO:0000269|PubMed:22275430}; Lipid-anchor {ECO:0000255}. Note=Enriched in lamellipodia. |
| Mouse PG classification | NA |
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