| Gene Information | |
|---|---|
| Gene Name | FLVCR1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 555 |
| Protein Names | Feline leukemia virus subgroup C receptor-related protein 1 (Feline leukemia virus subgroup C receptor) (hFLVCR) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000162769 ) |
| Evolutionary Stage | Cellular_organisms |
| AlphaFoldDB | Q9Y5Y0 |
| Gene Card | FLVCR1 |
| Uniprot ID | Q9Y5Y0 |
| Pfam | PF07690 |
| In ASD | no |
| Allosteric Prediction | no (-1.056533004) |
| Ortholog in Animals | Alpaca_ FLVCR1 ( ortholog_one2one ) Dog_ FLVCR1 ( ortholog_one2one ) GuineaPig_ FLVCR1 ( ortholog_one2one ) Macaque_ FLVCR1 ( ortholog_one2one ) Mouse_ Flvcr1 ( ortholog_one2one ) Pig_ FLVCR1 ( ortholog_one2one ) Rat_ Flvcr1 ( ortholog_one2one ) Rabbit_ FLVCR1 ( ortholog_one2one ) |
| Ohnologs | FLVCR2 |
| Paralogs | FLVCR2, CFAP276, SLC49A4, SLC49A3 |
| Tissue | NA |
| Tissue Specificity | Found all hematopoietic tissues including peripheral blood lymphocytes. Some expression is found in pancreas and kidney. {ECO:0000269|PubMed:10400745}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11120047 rs267606820 rs267606821 rs753000469 rs267606819 rs1558121050 rs3207090 |
| Subcellular location [CC] | [Isoform 1]: Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.; [Isoform 2]: Mitochondrion membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Mouse PG classification | LPG |
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