| Gene Information | |
|---|---|
| Gene Name | PHF6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 365 |
| Protein Names | PHD finger protein 6 (PHD-like zinc finger protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000156531 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8IWS0 |
| Gene Card | PHF6 |
| Uniprot ID | Q8IWS0 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.441248045) |
| Ortholog in Animals | Alpaca_ PHF6 ( ortholog_one2one ) Dog_ PHF6 ( ortholog_one2one ) GuineaPig_ PHF6 ( ortholog_one2one ) Macaque_ PHF6 ( ortholog_one2one ) Mouse_ Phf6 ( ortholog_one2one ) Pig_ PHF6 ( ortholog_one2one ) Rat_ Phf6 ( ortholog_one2one ) Rabbit_ PHF6 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PHF11, PHF7, G2E3 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:12415272}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);0.025(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4NN2 (X-ray 1.47A ) 4R7A (X-ray 1.85A ) |
| DBSNP | rs132630299 rs132630298 rs104894918 rs104894917 rs104894919 rs587777489 |
| Subcellular location [CC] | Nucleus. Nucleus, nucleolus. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:20813266}. Note=Nuclear, it particularly localizes to the nucleolus. |
| Mouse PG classification | NA |
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