| Gene Information | |
|---|---|
| Gene Name | NUDT3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 172 |
| Protein Names | Diphosphoinositol polyphosphate phosphohydrolase 1 (DIPP-1) (EC 3.6.1.52) (Diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 1) (EC 3.6.1.-) (Nucleoside diphosphate-linked moiety X motif 3) (Nudix motif 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000272325 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O95989 |
| Gene Card | NUDT3 |
| Uniprot ID | O95989 |
| Pfam | PF00293 |
| In ASD | no |
| Allosteric Prediction | no (-0.906647559) |
| Ortholog in Animals | Alpaca_ NUDT3 ( ortholog_one2one ) Dog_ NUDT3 ( ortholog_one2one ) GuineaPig_ NUDT3 ( ortholog_one2one ) Mouse_ Nudt3 ( ortholog_one2one ) Pig_ NUDT3 ( ortholog_one2one ) Rat_ Nudt3 ( ortholog_one2one ) Rabbit_ NUDT3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NUDT11, NUDT10, NUDT4, NUDT4B |
| Tissue | NA |
| Tissue Specificity | Widely expressed. Expressed at higher level in brain, heart, pancreas and liver. Also expressed in placenta, lung and kidney. {ECO:0000269|PubMed:9822604}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2FVV (X-ray 1.25A ) 2Q9P (X-ray 1.65A ) 6PCK (X-ray 1.20A ) 6PCL (X-ray 1.30A ) 6WO7 (X-ray 1.40A ) 6WO8 (X-ray 1.70A ) 6WO9 (X-ray 2.00A ) 6WOA (X-ray 1.50A ) 6WOB (X-ray 1.45A ) 6WOC (X-ray 1.35A ) 6WOD (X-ray 1.35A ) 6WOE (X-ray 1.40A ) 6WOF (X-ray 1.60A ) 6WOG (X-ray 1.50A ) 6WOH (X-ray 1.70A ) 6WOI (X-ray 1.50A ) 7TN4 (X-ray 1.85A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000305}. |
| Mouse PG classification | NA |
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