Gene Information
Gene NameFKSG8
OrganismHomo sapiens (Human)
Gene Length212
Protein NamesSentrin-specific protease 8 (EC 3.4.22.-) (Deneddylase-1) (NEDD8-specific protease 1) (Protease, cysteine 2) (Sentrin/SUMO-specific protease SENP8)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ96LD8
Gene CardSENP8
Uniprot IDQ96LD8
PfamPF02902
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityBroadly expressed, with highest levels in kidney and pancreas. {ECO:0000269|PubMed:12730221}.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);NULL(Rat);0.1(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 1XT9  (X-ray  2.20A  2BKQ  (X-ray  2.00A  2BKR  (X-ray  1.90A 
DBSNP rs930871 
Subcellular location [CC]NA
Mouse PG classificationNA
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