| Gene Information | |
|---|---|
| Gene Name | FITM2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 262 |
| Protein Names | Acyl-coenzyme A diphosphatase FITM2 (EC 3.6.1.-) (Fat storage-inducing transmembrane protein 2) (Fat-inducing protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000197296 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | Q8N6M3 |
| Gene Card | FITM2 |
| Uniprot ID | Q8N6M3 |
| Pfam | PF10261 |
| In ASD | no |
| Allosteric Prediction | no (-1.289849673) |
| Ortholog in Animals | Alpaca_ FITM2 ( ortholog_one2one ) Dog_ FITM2 ( ortholog_one2one ) GuineaPig_ FITM2 ( ortholog_one2one ) Macaque_ FITM2 ( ortholog_one2one ) Mouse_ Fitm2 ( ortholog_one2one ) Pig_ FITM2 ( ortholog_one2one ) Rat_ Fitm2 ( ortholog_one2one ) Rabbit_ FITM2 ( ortholog_one2one ) |
| Ohnologs | FITM1 |
| Paralogs | FITM1 |
| Tissue | NA |
| Tissue Specificity | Widely expressed. {ECO:0000269|PubMed:18160536}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs765281145 |
| Subcellular location [CC] | Endoplasmic reticulum membrane {ECO:0000255|HAMAP-Rule:MF_03230, ECO:0000269|PubMed:18160536}; Multi-pass membrane protein {ECO:0000255|HAMAP-Rule:MF_03230}. |
| Mouse PG classification | NA |
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