Gene Information | |
---|---|
Gene Name | FISH |
Organism | Homo sapiens (Human) |
Gene Length | 1133 |
Protein Names | SH3 and PX domain-containing protein 2A (Adapter protein TKS5) (Five SH3 domain-containing protein) (SH3 multiple domains protein 1) (Tyrosine kinase substrate with five SH3 domains) |
Target Name | NA |
Target Type | NA |
Gene Age | NA |
Evolutionary Stage | NA |
AlphaFoldDB | Q5TCZ1 |
Gene Card | SH3PXD2A |
Uniprot ID | Q5TCZ1 |
Pfam | PF00787; PF00018 |
In ASD | no |
Allosteric Prediction | NA |
Ortholog in Animals | NA |
Ohnologs | NA |
Paralogs | NA |
Tissue | NA |
Tissue Specificity | Found in several cancer cell lines, particularly invasive breast carcinomas and melanomas. {ECO:0000269|PubMed:15710328}. |
Pharmacological Animal Models | NA |
Gene Ontology (biological process) |
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Gene Ontology (cellular component) |
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Gene Ontology (molecular function) |
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PDB | 2DNU (NMR - ) 2EGA (NMR - ) 2EGC (NMR - ) 2EKH (NMR - ) |
DBSNP | rs11818820 rs3781365 rs12764700 |
Subcellular location [CC] | Cytoplasm. Cell projection, podosome. Note=Cytoplasmic in normal cells and localizes to podosomes in SRC-transformed cells. |
Mouse PG classification | NA |
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