| Gene Information | |
|---|---|
| Gene Name | FIGNL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 674 |
| Protein Names | Fidgetin-like protein 1 (EC 3.6.4.-) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1292 ( ENSG00000132436 ) |
| Evolutionary Stage | Euk_Archaea |
| AlphaFoldDB | Q6PIW4 |
| Gene Card | FIGNL1 |
| Uniprot ID | Q6PIW4 |
| Pfam | PF00004; PF09336 |
| In ASD | no |
| Allosteric Prediction | no (-0.778516304) |
| Ortholog in Animals | Dog_ FIGNL1 ( ortholog_one2one ) GuineaPig_ FIGNL1 ( ortholog_one2one ) Macaque_ FIGNL1 ( ortholog_one2one ) Mouse_ Fignl1 ( ortholog_one2one ) Pig_ FIGNL1 ( ortholog_one2one ) Rat_ Fignl1 ( ortholog_one2one ) Rabbit_ FIGNL1 ( ortholog_one2one ) |
| Ohnologs | FIGN |
| Paralogs | FIGNL2, VPS4A, FIGN, ATAD1, KATNAL2, SPAST, VPS4B, KATNAL1, KATNA1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3D8B (X-ray 2.00A ) |
| DBSNP | rs10235371 rs35929700 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:23754376}. Cytoplasm {ECO:0000250|UniProtKB:Q8BPY9}. Cytoplasm, perinuclear region {ECO:0000250|UniProtKB:Q8BPY9}. Note=Together with RAD51 and a subset of H2A histone proteins, redistributed in discrete nuclear DNA damage-induced foci after ionizing radiation (IR) treatment (PubMed:23754376). |
| Mouse PG classification | NA |
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