| Gene Information | |
|---|---|
| Gene Name | FIGLA |
| Organism | Homo sapiens (Human) |
| Gene Length | 219 |
| Protein Names | Factor in the germline alpha (FIGalpha) (Class C basic helix-loop-helix protein 8) (bHLHc8) (Folliculogenesis-specific basic helix-loop-helix protein) (Transcription factor FIGa) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 810 ( ENSG00000183733 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q6QHK4 |
| Gene Card | FIGLA |
| Uniprot ID | Q6QHK4 |
| Pfam | PF00010 |
| In ASD | no |
| Allosteric Prediction | no (-1.516986846) |
| Ortholog in Animals | Alpaca_ FIGLA ( ortholog_one2one ) Dog_ FIGLA ( ortholog_one2one ) GuineaPig_ FIGLA ( ortholog_one2one ) Macaque_ FIGLA ( ortholog_one2one ) Mouse_ Figla ( ortholog_one2one ) Pig_ FIGLA ( ortholog_one2one ) Rat_ Figla ( ortholog_one2one ) Rabbit_ FIGLA ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | TWIST2, SCX, PTF1A, FERD3L, BHLHA9, TWIST1, TCF23, HAND2, MSC, TCF15, HAND1, TCF24, TCF21 |
| Tissue | NA |
| Tissue Specificity | Germ cells. Expressed in the fetal ovary, but not by a range of other tissues. Expression increases across mid-gestation, rising some 40-fold by the time of primordial follicle formation. {ECO:0000269|PubMed:12468641, ECO:0000269|PubMed:15044608}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs71647803 rs7566476 |
| Subcellular location [CC] | Nucleus {ECO:0000305}. |
| Mouse PG classification | NA |
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