| Gene Information | |
|---|---|
| Gene Name | IFITM5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 132 |
| Protein Names | Interferon-induced transmembrane protein 5 (Bone-restricted interferon-induced transmembrane protein-like protein) (BRIL) (Dispanin subfamily A member 1) (DSPA1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000206013 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | A6NNB3 |
| Gene Card | IFITM5 |
| Uniprot ID | A6NNB3 |
| Pfam | PF04505 |
| In ASD | no |
| Allosteric Prediction | no (-1.497956025) |
| Ortholog in Animals | Alpaca_ IFITM5 ( ortholog_one2one ) Dog_ IFITM5 ( ortholog_one2one ) GuineaPig_ IFITM5 ( ortholog_one2one ) Macaque_ IFITM5 ( ortholog_one2one ) Mouse_ Ifitm5 ( ortholog_one2one ) Pig_ IFITM5 ( ortholog_one2one ) Rat_ Ifitm5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | IFITM2, IFITM3, IFITM1, IFITM10 |
| Tissue | bone.marrow |
| Tissue Specificity | Detected in bone (PubMed:24058703). Detected in osteoblasts and fibroblasts (at protein level) (PubMed:24519609). Detected in bone (PubMed:24058703). Detected in osteoblasts and fibroblasts (PubMed:24519609). {ECO:0000269|PubMed:24058703, ECO:0000269|PubMed:24519609}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs57285449 rs786201032 |
| Subcellular location [CC] | Cell membrane {ECO:0000269|PubMed:24519609}; Multi-pass membrane protein {ECO:0000255}. |
| Mouse PG classification | HPG |
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