| Gene Information | |
|---|---|
| Gene Name | FHL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 279 |
| Protein Names | Four and a half LIM domains protein 2 (FHL-2) (LIM domain protein DRAL) (Skeletal muscle LIM-protein 3) (SLIM-3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 886 ( ENSG00000115641 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q14192 |
| Gene Card | FHL2 |
| Uniprot ID | Q14192 |
| Pfam | PF00412 |
| In ASD | no |
| Allosteric Prediction | no (-0.695213642) |
| Ortholog in Animals | Alpaca_ FHL2 ( ortholog_one2one ) Dog_ FHL2 ( ortholog_one2one ) GuineaPig_ FHL2 ( ortholog_one2one ) Macaque_ FHL2 ( ortholog_one2one ) Mouse_ Fhl2 ( ortholog_one2one ) Rat_ Fhl2 ( ortholog_one2one ) Rabbit_ FHL2 ( ortholog_one2one ) |
| Ohnologs | FHL1, FHL5, FHL3 |
| Paralogs | FHL5, FHL3 |
| Tissue | ovary |
| Tissue Specificity | Expressed in skeletal muscle and heart. {ECO:0000269|PubMed:11813260}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1X4K (NMR - ) 1X4L (NMR - ) 2D8Z (NMR - ) 2MIU (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:11813260, ECO:0000269|PubMed:16652157}. Nucleus {ECO:0000269|PubMed:11813260, ECO:0000269|PubMed:16652157}. Cytoplasm, myofibril, sarcomere, Z line {ECO:0000250|UniProtKB:O35115}. |
| Mouse PG classification | NA |
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