| Gene Information | |
|---|---|
| Gene Name | TFDP1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 410 |
| Protein Names | Transcription factor Dp-1 (DRTF1-polypeptide 1) (DRTF1) (E2F dimerization partner 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000198176 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q14186 |
| Gene Card | TFDP1 |
| Uniprot ID | Q14186 |
| Pfam | PF08781; PF02319 |
| In ASD | no |
| Allosteric Prediction | no (-0.017133851) |
| Ortholog in Animals | Alpaca_ TFDP1 ( ortholog_one2one ) Dog_ TFDP1 ( ortholog_one2one ) GuineaPig_ TFDP1 ( ortholog_one2one ) Macaque_ TFDP1 ( ortholog_one2one ) Mouse_ Tfdp1 ( ortholog_one2one ) Pig_ TFDP1 ( ortholog_one2one ) Rat_ Tfdp1 ( ortholog_one2one ) Rabbit_ TFDP1 ( ortholog_one2one ) |
| Ohnologs | TFDP3, TFDP2 |
| Paralogs | TFDP3, TFDP2 |
| Tissue | NA |
| Tissue Specificity | Highest levels in muscle. Also expressed in brain, placenta, liver and kidney. Lower levels in lung and pancreas. Not detected in heart. |
| Pharmacological Animal Models | NULL(Chimpanzee);0.069500(Mouse);0.005185(Rat);0.051915(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2AZE (X-ray 2.55A ) 5GOW (NMR - ) 5TUU (X-ray 2.25A ) 5TUV (X-ray 2.90A ) |
| DBSNP | rs4150823 |
| Subcellular location [CC] | Nucleus {ECO:0000250|UniProtKB:Q08639}. Cytoplasm {ECO:0000250|UniProtKB:Q08639}. Note=Shuttles between the cytoplasm and nucleus and translocates into the nuclear compartment upon heterodimerization with E2F1. {ECO:0000250|UniProtKB:Q08639}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |