| Gene Information | |
|---|---|
| Gene Name | FGFRL1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 504 |
| Protein Names | Fibroblast growth factor receptor-like 1 (FGF receptor-like protein 1) (FGF homologous factor receptor) (FGFR-like protein) (Fibroblast growth factor receptor 5) (FGFR-5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000127418 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q8N441 |
| Gene Card | FGFRL1 |
| Uniprot ID | Q8N441 |
| Pfam | PF07679 |
| In ASD | no |
| Allosteric Prediction | no (-0.722470991) |
| Ortholog in Animals | Alpaca_ FGFRL1 ( ortholog_one2one ) Dog_ FGFRL1 ( ortholog_one2one ) GuineaPig_ FGFRL1 ( ortholog_one2one ) Macaque_ FGFRL1 ( ortholog_one2one ) Mouse_ Fgfrl1 ( ortholog_one2one ) Pig_ FGFRL1 ( ortholog_one2one ) Rat_ Fgfrl1 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | MCRIP2, MCRIP1 |
| Tissue | NA |
| Tissue Specificity | Expressed preferentially in cartilaginous tissues and pancreas. Highly expressed in the liver, kidney, heart, brain and skeletal muscle. Weakly expressed in the lung, small intestine and spleen. {ECO:0000269|PubMed:11031111, ECO:0000269|PubMed:11267671, ECO:0000269|PubMed:11418238}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs4647930 rs4647932 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:12813049}; Single-pass type I membrane protein {ECO:0000269|PubMed:12813049}. Note=Predominantly localized in the plasma membrane but also detected in the Golgi and in secretory vesicles. |
| Mouse PG classification | NA |
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