| Gene Information | |
|---|---|
| Gene Name | RETN |
| Organism | Homo sapiens (Human) |
| Gene Length | 108 |
| Protein Names | Resistin (Adipose tissue-specific secretory factor) (ADSF) (C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein) (Cysteine-rich secreted protein A12-alpha-like 2) (Cysteine-rich secreted protein FIZZ3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 454 ( ENSG00000104918 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9HD89 |
| Gene Card | RETN |
| Uniprot ID | Q9HD89 |
| Pfam | PF06954 |
| In ASD | no |
| Allosteric Prediction | yes (0.11812464) |
| Ortholog in Animals | Alpaca_ RETN ( ortholog_one2one ) Dog_ RETN ( ortholog_one2one ) GuineaPig_ RETN ( ortholog_one2one ) Mouse_ Retn ( ortholog_one2one ) Pig_ RETN ( ortholog_one2one ) Rat_ Retn ( ortholog_one2one ) Rabbit_ RETN ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | RETNLB |
| Tissue | bone.marrow, lung, spleen, whole.blood |
| Tissue Specificity | Expressed in white adipose tissue (at protein level) (PubMed:11201732). Widely expressed, with particularly strong expression in lung, bone marrow, breast and peripheral blood (PubMed:15248836). Expressed strongly in bone marrow and at lower levels in lung, but not detected in other tissues (PubMed:15064728). Isoform 2 is detected in adipose tissue, bone marrow, brain, lung, peripheral blood, placenta and thymus (PubMed:15248836). {ECO:0000269|PubMed:11201732, ECO:0000269|PubMed:15064728, ECO:0000269|PubMed:15248836}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | NA |
| Subcellular location [CC] | Secreted {ECO:0000250|UniProtKB:Q99P87}. |
| Mouse PG classification | HPG |
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