| Gene Information | |
|---|---|
| Gene Name | QSOX2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 698 |
| Protein Names | Sulfhydryl oxidase 2 (EC 1.8.3.2) (Neuroblastoma-derived sulfhydryl oxidase) (Quiescin Q6-like protein 1) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000165661 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q6ZRP7 |
| Gene Card | QSOX2 |
| Uniprot ID | Q6ZRP7 |
| Pfam | PF04777; PF18371; PF18108; PF00085 |
| In ASD | no |
| Allosteric Prediction | no (-1.139112155) |
| Ortholog in Animals | Alpaca_ QSOX2 ( ortholog_one2one ) Dog_ QSOX2 ( ortholog_one2one ) GuineaPig_ QSOX2 ( ortholog_one2one ) Macaque_ QSOX2 ( ortholog_one2one ) Mouse_ Qsox2 ( ortholog_one2one ) Pig_ QSOX2 ( ortholog_one2one ) Rat_ Qsox2 ( ortholog_one2one ) |
| Ohnologs | QSOX1 |
| Paralogs | QSOX1 |
| Tissue | NA |
| Tissue Specificity | Expressed in pancreas, brain, placenta, kidney, heart and fetal tissues. Weakly expressed in lung, liver and skeletal muscles. {ECO:0000269|PubMed:14633699}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12380852 |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:14633699}; Single-pass membrane protein {ECO:0000269|PubMed:14633699}. Secreted {ECO:0000269|PubMed:14633699}. Cell membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Nucleus membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}. Note=Seems to be predominantly targeted to the nuclear and outer plasma membrane. |
| Mouse PG classification | NA |
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