| Gene Information | |
|---|---|
| Gene Name | FGF6 |
| Organism | Homo sapiens (Human) |
| Gene Length | 208 |
| Protein Names | Fibroblast growth factor 6 (FGF-6) (Heparin secretory-transforming protein 2) (HST-2) (HSTF-2) (Heparin-binding growth factor 6) (HBGF-6) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000111241 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P10767 |
| Gene Card | FGF6 |
| Uniprot ID | P10767 |
| Pfam | PF00167 |
| In ASD | no |
| Allosteric Prediction | no (-0.342117129) |
| Ortholog in Animals | Alpaca_ FGF6 ( ortholog_one2one ) Dog_ FGF6 ( ortholog_one2one ) GuineaPig_ FGF6 ( ortholog_one2one ) Macaque_ FGF6 ( ortholog_one2one ) Mouse_ Fgf6 ( ortholog_one2one ) Pig_ FGF6 ( ortholog_one2one ) Rat_ Fgf6 ( ortholog_one2one ) Rabbit_ FGF6 ( ortholog_one2one ) |
| Ohnologs | FGF11, FGF4, FGF12, FGF3 |
| Paralogs | FGF1, FGF16, FGF14, FGF21, FGF3, FGF10, FGF5, FGF9, FGF7, FGF22, FGF23, FGF19, FGF17, FGF13, FGF8, FGF18, FGF11, FGF12, FGF20, FGF2, FGF4 |
| Tissue | artery |
| Tissue Specificity | Leukemia cell lines with platelet/ megakaryocytic differentiation potential. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs11613495 rs17183529 rs7961645 rs17183778 |
| Subcellular location [CC] | Secreted, extracellular space. |
| Mouse PG classification | NA |
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