| Gene Information | |
|---|---|
| Gene Name | CACNB4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 520 |
| Protein Names | Voltage-dependent L-type calcium channel subunit beta-4 (CAB4) (Calcium channel voltage-dependent subunit beta 4) |
| Target Name | voltage-dependent l-type calcium channel |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000182389 ) |
| Evolutionary Stage | Opisthokonta |
| AlphaFoldDB | O00305 |
| Gene Card | CACNB4 |
| Uniprot ID | O00305 |
| Pfam | PF00625; PF12052 |
| In ASD | no |
| Allosteric Prediction | yes (1.009862721) |
| Ortholog in Animals | Alpaca_ CACNB4 ( ortholog_one2one ) Dog_ CACNB4 ( ortholog_one2one ) GuineaPig_ CACNB4 ( ortholog_one2one ) Macaque_ CACNB4 ( ortholog_one2one ) Mouse_ Cacnb4 ( ortholog_one2one ) Pig_ CACNB4 ( ortholog_one2one ) Rat_ Cacnb4 ( ortholog_one2one ) |
| Ohnologs | CACNB1, CACNB2, CACNB3 |
| Paralogs | CACNB3, CACNB2, CACNB1 |
| Tissue | brain, cerebellar.hemisphere, cerebellum |
| Tissue Specificity | Expressed predominantly in the cerebellum and kidney. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2D46 (NMR - ) |
| DBSNP | rs1805031 |
| Subcellular location [CC] | NA |
| Mouse PG classification | HPG |
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