| Gene Information | |
|---|---|
| Gene Name | FTCD |
| Organism | Homo sapiens (Human) |
| Gene Length | 541 |
| Protein Names | Formimidoyltransferase-cyclodeaminase (Formiminotransferase-cyclodeaminase) (FTCD) (LCHC1) [Includes: Glutamate formimidoyltransferase (EC 2.1.2.5) (Glutamate formiminotransferase) (Glutamate formyltransferase); Formimidoyltetrahydrofolate cyclodeaminase (EC 4.3.1.4) (Formiminotetrahydrofolate cyclodeaminase)] |
| Target Name | formimidoyltransferase-cyclodeaminase |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000160282 ) 3 ( ENSG00000281775 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | O95954 |
| Gene Card | FTCD |
| Uniprot ID | O95954 |
| Pfam | PF02971; PF04961; PF07837 |
| In ASD | no |
| Allosteric Prediction | yes (0.476843144) |
| Ortholog in Animals | Dog_ FTCD ( ortholog_one2one ) GuineaPig_ FTCD ( ortholog_one2one ) Macaque_ FTCD ( ortholog_one2one ) Mouse_ Ftcd ( ortholog_one2one ) Pig_ FTCD ( ortholog_one2one ) Rat_ Ftcd ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FTCDNL1 |
| Tissue | kidney, liver |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs28941768 rs119469015 |
| Subcellular location [CC] | Cytoplasm, cytosol {ECO:0000250|UniProtKB:Q9YH58}. Golgi apparatus {ECO:0000250|UniProtKB:Q9YH58}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:16534631}. Note=More abundantly located around the mother centriole. {ECO:0000269|PubMed:16534631}. |
| Mouse PG classification | NA |
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