| Gene Information | |
|---|---|
| Gene Name | E2F2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 437 |
| Protein Names | Transcription factor E2F2 (E2F-2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000007968 ) 3 ( ENSG00000282899 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q14209 |
| Gene Card | E2F2 |
| Uniprot ID | Q14209 |
| Pfam | PF16421; PF02319 |
| In ASD | no |
| Allosteric Prediction | yes (0.245786361) |
| Ortholog in Animals | Alpaca_ E2F2 ( ortholog_one2one ) Dog_ E2F2 ( ortholog_one2one ) GuineaPig_ E2F2 ( ortholog_one2one ) Macaque_ E2F2 ( ortholog_one2one ) Mouse_ E2f2 ( ortholog_one2one ) Pig_ E2F2 ( ortholog_one2one ) Rat_ E2f2 ( ortholog_one2one ) Rabbit_ E2F2 ( ortholog_one2one ) |
| Ohnologs | E2F1, E2F3, E2F6 |
| Paralogs | E2F5, E2F6, E2F3, E2F8, E2F1, E2F4, E2F7 |
| Tissue | bone.marrow |
| Tissue Specificity | Highest level of expression is found in placenta, low levels are found in lung. Found as well in many immortalized cell lines derived from tumor samples. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002657(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 1N4M (X-ray 2.20A ) |
| DBSNP | rs2229297 rs2075995 |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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