| Gene Information | |
|---|---|
| Gene Name | FDXR |
| Organism | Homo sapiens (Human) |
| Gene Length | 491 |
| Protein Names | NADPH:adrenodoxin oxidoreductase, mitochondrial (AR) (Adrenodoxin reductase) (EC 1.18.1.6) (Ferredoxin--NADP(+) reductase) (Ferredoxin reductase) |
| Target Name | nadph:adrenodoxin oxidoreductase, mitochondrial |
| Target Type | NA |
| Gene Age | >4290 ( ENSG00000161513 ) |
| Evolutionary Stage | Euk+Bac |
| AlphaFoldDB | P22570 |
| Gene Card | FDXR |
| Uniprot ID | P22570 |
| Pfam | PF07992 |
| In ASD | no |
| Allosteric Prediction | yes (0.525358866) |
| Ortholog in Animals | Alpaca_ FDXR ( ortholog_one2one ) Dog_ FDXR ( ortholog_one2one ) GuineaPig_ FDXR ( ortholog_one2one ) Macaque_ FDXR ( ortholog_one2one ) Pig_ FDXR ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | DPYD, DHODH |
| Tissue | adrenal.gland |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs28365947 rs690514 rs35692345 rs35072974 rs34038065 rs34118765 rs35660143 rs35696549 rs35769464 |
| Subcellular location [CC] | Mitochondrion inner membrane {ECO:0000250|UniProtKB:P48360}; Peripheral membrane protein {ECO:0000305}. |
| Mouse PG classification | NA |
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