| Gene Information | |
|---|---|
| Gene Name | ASIC4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 539 |
| Protein Names | Acid-sensing ion channel 4 (ASIC4) (Amiloride-sensitive cation channel 4) (Amiloride-sensitive cation channel 4, pituitary) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000072182 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96FT7 |
| Gene Card | ASIC4 |
| Uniprot ID | Q96FT7 |
| Pfam | PF00858 |
| In ASD | no |
| Allosteric Prediction | no (-0.332729379) |
| Ortholog in Animals | Alpaca_ ASIC4 ( ortholog_one2one ) Dog_ ASIC4 ( ortholog_one2one ) GuineaPig_ ASIC4 ( ortholog_one2one ) Macaque_ ASIC4 ( ortholog_one2one ) Mouse_ Asic4 ( ortholog_one2one ) Pig_ ASIC4 ( ortholog_one2one ) Rat_ Asic4 ( ortholog_one2one ) Rabbit_ ASIC4 ( ortholog_one2one ) |
| Ohnologs | ASIC2, ASIC1, ASIC3, SCNN1D |
| Paralogs | ASIC1, ASIC5, SCNN1B, SCNN1G, SCNN1A, SCNN1D, ASIC2, ASIC3 |
| Tissue | pituitary.gland |
| Tissue Specificity | Expressed in pituitary gland. Weakly expressed in brain, vestibular system and organ of Corti. {ECO:0000269|PubMed:10852210}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs6436153 rs11689281 rs11695248 |
| Subcellular location [CC] | Membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. |
| Mouse PG classification | NA |
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