| Gene Information | |
|---|---|
| Gene Name | ATG4A |
| Organism | Homo sapiens (Human) |
| Gene Length | 398 |
| Protein Names | Cysteine protease ATG4A (EC 3.4.22.-) (AUT-like 2 cysteine endopeptidase) (Autophagy-related cysteine endopeptidase 2) (Autophagin-2) (Autophagy-related protein 4 homolog A) (HsAPG4A) (hAPG4A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000101844 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8WYN0 |
| Gene Card | ATG4A |
| Uniprot ID | Q8WYN0 |
| Pfam | PF20166; PF03416 |
| In ASD | no |
| Allosteric Prediction | no (-0.358427822) |
| Ortholog in Animals | Alpaca_ ATG4A ( ortholog_one2one ) Dog_ ATG4A ( ortholog_one2one ) GuineaPig_ ATG4A ( ortholog_one2one ) Macaque_ ATG4A ( ortholog_one2one ) Mouse_ Atg4a-ps ( ortholog_one2many ) Mouse_ Atg4a ( ortholog_one2many ) Pig_ ATG4A ( ortholog_one2one ) Rat_ AABR07040864.1 ( ortholog_one2one ) Rabbit_ ATG4A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ATG4B, ATG4C, ATG4D |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.027573(Mouse);NULL(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | 2P82 (X-ray 2.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000250|UniProtKB:Q8BGE6}. |
| Mouse PG classification | NA |
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