| Gene Information | |
|---|---|
| Gene Name | FCGBP |
| Organism | Homo sapiens (Human) |
| Gene Length | 5405 |
| Protein Names | IgGFc-binding protein (Fcgamma-binding protein antigen) (FcgammaBP) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 36 ( ENSG00000275395 ) 3 ( ENSG00000281123 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | NA |
| Gene Card | FCGBP |
| Uniprot ID | Q9Y6R7 |
| Pfam | PF08742; PF17517; PF01826; PF12714; PF00094 |
| In ASD | no |
| Allosteric Prediction | no (-1.322182317) |
| Ortholog in Animals | Alpaca_ FCGBP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | CHRDL1, MUC5B, KCP, CHRDL2, CHRD, VWF, VWCE, OTOGL, MUC6, MUC5AC, OTOG, ZAN, BMPER, CRIM1, MUC2, MUC19, VWC2L, VWC2, TECTA |
| Tissue | small.intestine, transverse.colon |
| Tissue Specificity | Mainly expressed in placenta and colon epithelium. Expressed in thyroid, and down-regulated in thyroid carcinomas. Present in serum, with higher levels in patients with various autoimmune diseases (at protein level). {ECO:0000269|PubMed:11600203, ECO:0000269|PubMed:12208673, ECO:0000269|PubMed:9182547}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs34181317 rs34939346 rs35338934 rs35922811 rs34254649 rs11083543 rs36106401 rs2909229 rs34938990 rs7248839 rs7249743 rs885723 rs140171218 rs1176978283 rs2542316 rs3746009 rs1290971390 rs2542318 rs3746009 rs1975181 rs6508919 rs3746013 rs741143 |
| Subcellular location [CC] | Secreted {ECO:0000305}. |
| Mouse PG classification | NA |
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