| Gene Information | |
|---|---|
| Gene Name | FCER1A |
| Organism | Homo sapiens (Human) |
| Gene Length | 257 |
| Protein Names | High affinity immunoglobulin epsilon receptor subunit alpha (Fc-epsilon RI-alpha) (FcERI) (IgE Fc receptor subunit alpha) |
| Target Name | high affinity immunoglobulin epsilon receptor subunit alpha |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000179639 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | P12319 |
| Gene Card | FCER1A |
| Uniprot ID | P12319 |
| Pfam | PF13895 |
| In ASD | no |
| Allosteric Prediction | yes (0.484927502) |
| Ortholog in Animals | Alpaca_ FCER1A ( ortholog_one2one ) Dog_ FCER1A ( ortholog_one2one ) Macaque_ FCER1A ( ortholog_one2one ) Mouse_ Fcer1a ( ortholog_one2one ) Pig_ FCER1A ( ortholog_one2one ) Rat_ Fcer1a ( ortholog_one2one ) Rabbit_ FCER1A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | PECAM1, FCGR3B, FCGR2A, FCGR2B, FCGR3A, FCGR2C, FCGR1A, C17orf99, FCRLA, FCRLB, FCRL6, FCRL5, FCRL4, MILR1, FCRL2, FCRL3, FCRL1 |
| Tissue | zone.of.skin |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 1F2Q (X-ray 2.40A ) 1F6A (X-ray 3.50A ) 1J86 (X-ray 3.20A ) 1J87 (X-ray 3.20A ) 1J88 (X-ray 3.20A ) 1J89 (X-ray 4.10A ) 1RPQ (X-ray 3.00A ) 2Y7Q (X-ray 3.40A ) 7SHT (EM 7.29A ) |
| DBSNP | rs2298804 rs2298805 |
| Subcellular location [CC] | Cell membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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