| Gene Information | |
|---|---|
| Gene Name | FBXW12 |
| Organism | Homo sapiens (Human) |
| Gene Length | 464 |
| Protein Names | F-box/WD repeat-containing protein 12 (F-box and WD-40 domain-containing protein 12) (F-box only protein 35) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1714 ( ENSG00000164049 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q6X9E4 |
| Gene Card | FBXW12 |
| Uniprot ID | Q6X9E4 |
| Pfam | PF12937 |
| In ASD | no |
| Allosteric Prediction | no (-1.000313842) |
| Ortholog in Animals | Alpaca_ FBXW12 ( ortholog_one2one ) Dog_ FBXW12 ( ortholog_one2one ) Macaque_ FBXW12 ( ortholog_one2one ) Mouse_ Fbxw15 ( ortholog_one2many ) Mouse_ Fbxw27 ( ortholog_one2many ) Mouse_ Fbxw16 ( ortholog_one2many ) Mouse_ Fbxw26 ( ortholog_one2many ) Mouse_ Fbxw24 ( ortholog_one2many ) Mouse_ Fbxw19 ( ortholog_one2many ) Mouse_ Fbxw21 ( ortholog_one2many ) Mouse_ Fbxw18 ( ortholog_one2many ) Mouse_ Fbxw13 ( ortholog_one2many ) Mouse_ Fbxw14 ( ortholog_one2many ) Mouse_ Fbxw22 ( ortholog_one2many ) Mouse_ Fbxw28 ( ortholog_one2many ) Mouse_ Fbxw25 ( ortholog_one2many ) Mouse_ Fbxw20 ( ortholog_one2many ) Rat_ Fbxw12 ( ortholog_one2one ) Rabbit_ FBXW12 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FBXW11, WDR49, FBXO36, BTRC, FBXW8, PAAF1, WDR64, EFCAB8, WDR86, FBXO16, TRAF7, FBXW9, FBXW7, WDR54 |
| Tissue | NA |
| Tissue Specificity | Ubiquitously expressed. {ECO:0000269|PubMed:15040455}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs17080138 rs6442117 rs6784322 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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