Gene Information
Gene NameFBXO32
OrganismHomo sapiens (Human)
Gene Length355
Protein NamesF-box only protein 32 (Atrogin-1) (Muscle atrophy F-box protein) (MAFbx)
Target NameNA
Target TypeNA
Gene Age810 ( ENSG00000156804 )
Evolutionary StageEumetazoa
AlphaFoldDBQ969P5
Gene CardFBXO32
Uniprot IDQ969P5
PfamNA
In ASDno
Allosteric Predictionyes (0.036223976)
Ortholog in AnimalsAlpaca_ FBXO32 ( ortholog_one2one )
Dog_ FBXO32 ( ortholog_one2one )
GuineaPig_ FBXO32 ( ortholog_one2one )
Macaque_ FBXO32 ( ortholog_one2one )
Mouse_ Fbxo32 ( ortholog_one2one )
Pig_ FBXO32 ( ortholog_one2one )
Rat_ Fbxo32 ( ortholog_one2one )
Rabbit_ FBXO32 ( ortholog_one2one )
OhnologsFBXO25
ParalogsFBXO25
TissueNA
Tissue SpecificitySpecifically expressed in cardiac and skeletal muscle.
Pharmacological Animal ModelsNULL(Chimpanzee);0.001000(Mouse);0.003490(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP rs6988591  rs11786471  rs771939133 
Subcellular location [CC]Cytoplasm {ECO:0000269|PubMed:22249105, ECO:0000269|PubMed:26768247}. Nucleus {ECO:0000269|PubMed:22249105}. Note=Shuttles between cytoplasm and the nucleus.
Mouse PG classificationNA
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