| Gene Information | |
|---|---|
| Gene Name | FBXL5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 691 |
| Protein Names | F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000118564 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q9UKA1 |
| Gene Card | FBXL5 |
| Uniprot ID | Q9UKA1 |
| Pfam | PF12937; PF01814; PF13516 |
| In ASD | no |
| Allosteric Prediction | no (-0.62895478) |
| Ortholog in Animals | Alpaca_ FBXL5 ( ortholog_one2one ) Dog_ FBXL5 ( ortholog_one2one ) GuineaPig_ FBXL5 ( ortholog_one2one ) Macaque_ FBXL5 ( ortholog_one2one ) Mouse_ Fbxl5 ( ortholog_one2one ) Pig_ FBXL5 ( ortholog_one2one ) Rat_ Fbxl5 ( ortholog_one2one ) Rabbit_ FBXL5 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FBXL22, FBXL3, FBXL13, FBXL17, FBXL16, FBXL19, FBXL18, FBXL14, FBXL2, FBXL20, FBXL6, FBXL4, FBXL15, SKP2, FBXL7 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3U9J (X-ray 1.60A ) 3U9M (X-ray 1.95A ) 3V5X (X-ray 1.85A ) 3V5Y (X-ray 2.10A ) 3V5Z (X-ray 2.18A ) 6VCD (EM 3.00A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, perinuclear region {ECO:0000269|PubMed:17532294}. |
| Mouse PG classification | NA |
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