Gene Information
Gene NamePAK7
OrganismHomo sapiens (Human)
Gene Length719
Protein NamesSerine/threonine-protein kinase PAK 5 (EC 2.7.11.1) (p21-activated kinase 5) (PAK-5) (p21-activated kinase 7) (PAK-7)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ9P286
Gene CardPAK5
Uniprot IDQ9P286
PfamPF00786; PF00069
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityPredominantly expressed in brain.
Pharmacological Animal Models0.000730(Chimpanzee);0.001000(Mouse);NULL(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 2F57  (X-ray  1.80A 
DBSNP rs55923311  rs34280805  rs952665081  rs11700112  rs2297345  rs34102290  rs1484691555 
Subcellular location [CC]Mitochondrion. Cytoplasm. Nucleus. Note=Shuttles between the nucleus and the mitochondria, and mitochondrial localization is essential for the role in cell survival.
Mouse PG classificationNA
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