Gene Information
Gene NamePOMGNT1
OrganismHomo sapiens (Human)
Gene Length660
Protein NamesProtein O-linked-mannose beta-1,2-N-acetylglucosaminyltransferase 1 (POMGnT1) (EC 2.4.1.-) (UDP-GlcNAc:alpha-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I.2) (GnT I.2)
Target NameNA
Target TypeNA
Gene Age1064 ( ENSG00000085998 )
Evolutionary StageEukaryota
AlphaFoldDBQ8WZA1
Gene CardPOMGNT1
Uniprot IDQ8WZA1
PfamPF03071; PF15711
In ASDno
Allosteric Predictionno (-1.113109282)
Ortholog in AnimalsAlpaca_ POMGNT1 ( ortholog_one2one )
Dog_ POMGNT1 ( ortholog_one2one )
GuineaPig_ POMGNT1 ( ortholog_one2one )
Macaque_ POMGNT1 ( ortholog_one2one )
Mouse_ Pomgnt1 ( ortholog_one2one )
Pig_ POMGNT1 ( ortholog_one2one )
Rat_ Pomgnt1 ( ortholog_one2one )
Rabbit_ POMGNT1 ( ortholog_one2one )
OhnologsNA
ParalogsMGAT1
TissueNA
Tissue SpecificityConstitutively expressed. An additional weaker band is also detected in spinal cord, lymph node, and trachea. Expressed especially in astrocytes. Also expressed in immature and mature neurons. {ECO:0000269|PubMed:11709191, ECO:0000269|PubMed:11742540}.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5GGF  (X-ray  2.49A  )  5GGG  (X-ray  3.00A  )  5GGI  (X-ray  2.60A  )  5GGJ  (X-ray  1.42A  )  5GGK  (X-ray  1.30A  )  5GGL  (X-ray  1.27A  )  5GGN  (X-ray  1.21A  )  5GGO  (X-ray  1.50A  )  5GGP  (X-ray  1.60A  )  5XFC  (X-ray  1.40A  ) 
DBSNP rs886037949  rs886037947  rs386834030  rs386834032  rs386834036  rs17855359  rs386834010  rs386834037  rs200863680  rs193919336  rs762972459  rs386834011  rs28940869  rs267606960  rs28942068  rs886037948  rs17102066  rs193919335  rs74374973  rs267606962  rs6659553 
Subcellular location [CC]Golgi apparatus membrane {ECO:0000269|PubMed:17034757, ECO:0000303|PubMed:11709191};
Single-pass type II membrane protein {ECO:0000305|PubMed:11709191}.
Mouse PG classificationNA
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