| Gene Information | |
|---|---|
| Gene Name | FBXL2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 423 |
| Protein Names | F-box/LRR-repeat protein 2 (F-box and leucine-rich repeat protein 2) (F-box protein FBL2/FBL3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1488 ( ENSG00000153558 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q9UKC9 |
| Gene Card | FBXL2 |
| Uniprot ID | Q9UKC9 |
| Pfam | PF12937; PF13516 |
| In ASD | no |
| Allosteric Prediction | no (-0.618916307) |
| Ortholog in Animals | Alpaca_ FBXL2 ( ortholog_one2one ) Dog_ FBXL2 ( ortholog_one2one ) GuineaPig_ FBXL2 ( ortholog_one2one ) Macaque_ FBXL2 ( ortholog_one2one ) Mouse_ Fbxl2 ( ortholog_one2one ) Pig_ FBXL2 ( ortholog_one2one ) Rat_ Fbxl2 ( ortholog_one2one ) Rabbit_ FBXL2 ( ortholog_one2one ) |
| Ohnologs | FBXL20 |
| Paralogs | FBXL20, FBXL22, FBXL3, FBXL13, FBXL17, FBXL16, FBXL19, FBXL5, FBXL18, FBXL14, FBXL6, FBXL4, FBXL15, SKP2, FBXL7 |
| Tissue | NA |
| Tissue Specificity | Expressed in brain, heart, kidney, liver, lung, pancreas and placenta. {ECO:0000269|PubMed:10531037}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6O60 (X-ray 2.50A ) |
| DBSNP | NA |
| Subcellular location [CC] | Membrane {ECO:0000269|PubMed:15893726}; Lipid-anchor {ECO:0000269|PubMed:15893726}. |
| Mouse PG classification | NA |
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