| Gene Information | |
|---|---|
| Gene Name | PDZD4 |
| Organism | Homo sapiens (Human) |
| Gene Length | 769 |
| Protein Names | PDZ domain-containing protein 4 (PDZ domain-containing RING finger protein 4-like protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 544 ( ENSG00000067840 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q76G19 |
| Gene Card | PDZD4 |
| Uniprot ID | Q76G19 |
| Pfam | PF00595; PF02163 |
| In ASD | no |
| Allosteric Prediction | no (-1.920189468) |
| Ortholog in Animals | Alpaca_ PDZD4 ( ortholog_one2one ) Dog_ PDZD4 ( ortholog_one2one ) GuineaPig_ PDZD4 ( ortholog_one2one ) Macaque_ PDZD4 ( ortholog_one2one ) Mouse_ Pdzd4 ( ortholog_one2one ) Pig_ PDZD4 ( ortholog_one2one ) Rat_ Pdzd4 ( ortholog_one2one ) Rabbit_ PDZD4 ( ortholog_one2one ) |
| Ohnologs | PDZRN3, PDZRN4 |
| Paralogs | PDZRN4, PDZRN3 |
| Tissue | cerebral.cortex, brain |
| Tissue Specificity | Brain-specific. Expressed in fetal and adult brain. Up-regulated in synovial carcinomas. {ECO:0000269|PubMed:15077175}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs782272149 |
| Subcellular location [CC] | Cytoplasm, cell cortex {ECO:0000269|PubMed:15077175}. Note=Mainly localized under the plasma membrane. |
| Mouse PG classification | NA |
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