Gene Information
Gene NameCTSO
OrganismHomo sapiens (Human)
Gene Length321
Protein NamesCathepsin O (EC 3.4.22.42)
Target NameNA
Target TypeNA
Gene Age1488 ( ENSG00000256043 )
3 ( ENSG00000263238 )
Evolutionary StageEukaryota
AlphaFoldDBP43234
Gene CardCTSO
Uniprot IDP43234
PfamPF00112
In ASDno
Allosteric Predictionyes (0.061379943)
Ortholog in AnimalsAlpaca_ CTSO ( ortholog_one2one )
Dog_ CTSO ( ortholog_one2one )
GuineaPig_ CTSO ( ortholog_one2one )
Macaque_ CTSO ( ortholog_one2one )
Mouse_ Ctso ( ortholog_one2one )
Pig_ CTSO ( ortholog_one2one )
Rat_ Ctso ( ortholog_one2one )
Rabbit_ CTSO ( ortholog_one2one )
OhnologsNA
ParalogsCTSL, CTSV, CTSK, CTSH, TINAGL1, CTSW, CTSF, TINAG, CTSB, CTSC, CTSZ, CTSS
TissueNA
Tissue SpecificityExpressed in all tissues examined. High levels seen in the ovary, kidney and placenta while low levels seen in thymus and skeletal muscle.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Lysosome.
Mouse PG classificationNA
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