| Gene Information | |
|---|---|
| Gene Name | GIT2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 759 |
| Protein Names | ARF GTPase-activating protein GIT2 (ARF GAP GIT2) (Cool-interacting tyrosine-phosphorylated protein 2) (CAT-2) (CAT2) (G protein-coupled receptor kinase-interactor 2) (GRK-interacting protein 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000139436 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q14161 |
| Gene Card | GIT2 |
| Uniprot ID | Q14161 |
| Pfam | PF12796; PF01412; PF12205; PF16559; PF08518 |
| In ASD | no |
| Allosteric Prediction | no (-0.08182013) |
| Ortholog in Animals | Alpaca_ GIT2 ( ortholog_one2one ) Dog_ GIT2 ( ortholog_one2one ) GuineaPig_ GIT2 ( ortholog_one2one ) Macaque_ GIT2 ( ortholog_one2one ) Mouse_ Git2 ( ortholog_one2one ) Pig_ GIT2 ( ortholog_one2one ) Rat_ Git2 ( ortholog_one2one ) Rabbit_ GIT2 ( ortholog_one2one ) |
| Ohnologs | GIT1 |
| Paralogs | ASAP2, ASAP1, ACAP3, ARAP2, GIT1, ARAP3, AGFG1, ADAP1, SMAP1, AGAP1, ACAP2, AGAP3, AGAP4, AGAP6, AGAP9, AGAP5, ARFGAP1, ASAP3, APPL1, ARFGAP2, ARAP1, AGFG2, APPL2, ARFGAP3, ADAP2, SMAP2, AGAP2, ACAP1 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs9804905 rs925368 rs11068997 |
| Subcellular location [CC] | NA |
| Mouse PG classification | NA |
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