| Gene Information | |
|---|---|
| Gene Name | FREM2 |
| Organism | Homo sapiens (Human) |
| Gene Length | 3169 |
| Protein Names | FRAS1-related extracellular matrix protein 2 (ECM3 homolog) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000150893 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | NA |
| Gene Card | FREM2 |
| Uniprot ID | Q5SZK8 |
| Pfam | PF03160; PF19309 |
| In ASD | no |
| Allosteric Prediction | no (-1.296410185) |
| Ortholog in Animals | Alpaca_ FREM2 ( ortholog_one2one ) Dog_ FREM2 ( ortholog_one2one ) GuineaPig_ FREM2 ( ortholog_one2one ) Macaque_ FREM2 ( ortholog_one2one ) Mouse_ Frem2 ( ortholog_one2one ) Pig_ FREM2 ( ortholog_one2one ) Rat_ Frem2 ( ortholog_one2one ) Rabbit_ FREM2 ( ortholog_one2one ) |
| Ohnologs | FREM3 |
| Paralogs | FREM3, FRAS1, SLC8A1, FREM1, SLC8A3, SLC8A2, ADGRV1 |
| Tissue | kidney, thyroid |
| Tissue Specificity | NA |
| Pharmacological Animal Models | 0.000730(Chimpanzee);0.001000(Mouse);0.001000(Rat);0.100000(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs58363253 rs2496423 rs7327915 rs7329939 rs2496424 rs17058433 rs2496425 rs1868463 rs9603422 rs121434356 rs9548505 rs9548506 rs114837786 rs9548509 rs7996253 |
| Subcellular location [CC] | Cell membrane {ECO:0000305|PubMed:15838507}; Single-pass type I membrane protein {ECO:0000255}. |
| Mouse PG classification | HPG |
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