| Gene Information | |
|---|---|
| Gene Name | FAT10 |
| Organism | Homo sapiens (Human) |
| Gene Length | 165 |
| Protein Names | Ubiquitin D (Diubiquitin) (Ubiquitin-like protein FAT10) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | O15205 |
| Gene Card | UBD |
| Uniprot ID | O15205 |
| Pfam | PF00240 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Constitutively expressed in mature dendritic cells and B-cells. Mostly expressed in the reticuloendothelial system (e.g. thymus, spleen), the gastrointestinal system, kidney, lung and prostate gland. {ECO:0000269|PubMed:12730673, ECO:0000269|PubMed:9368598}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2MBE (NMR - ) 6GF1 (X-ray 1.93A ) 6GF2 (NMR - ) |
| DBSNP | rs2076484 rs2076485 rs2076486 rs2076487 rs17184290 rs8337 rs7757931 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:12730673, ECO:0000269|PubMed:19033385}. Cytoplasm {ECO:0000250}. Note=Accumulates in aggresomes under proteasome inhibition conditions. |
| Mouse PG classification | NA |
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