| Gene Information | |
|---|---|
| Gene Name | HES1 |
| Organism | Homo sapiens (Human) |
| Gene Length | 280 |
| Protein Names | Transcription factor HES-1 (Class B basic helix-loop-helix protein 39) (bHLHb39) (Hairy and enhancer of split 1) (Hairy homolog) (Hairy-like protein) (hHL) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 680 ( ENSG00000114315 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q14469 |
| Gene Card | HES1 |
| Uniprot ID | Q14469 |
| Pfam | PF07527; PF00010 |
| In ASD | no |
| Allosteric Prediction | no (-0.391343455) |
| Ortholog in Animals | Alpaca_ HES1 ( ortholog_one2one ) Dog_ HES1 ( ortholog_one2one ) GuineaPig_ HES1 ( ortholog_one2one ) Macaque_ HES1 ( ortholog_one2one ) Mouse_ Hes1 ( ortholog_one2one ) Pig_ HES1 ( ortholog_one2one ) Rat_ Hes1 ( ortholog_one2one ) Rabbit_ HES1 ( ortholog_one2one ) |
| Ohnologs | HES2, HES4 |
| Paralogs | HEYL, BHLHE40, HES5, HES4, HES7, HES3, HEY2, HEY1, HES2, HELT, HES6, BHLHE41 |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.038108(Rat);0.060000(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | 2MH3 (NMR - ) 7C4O (NMR - ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus. |
| Mouse PG classification | NA |
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