| Gene Information | |
|---|---|
| Gene Name | FANCN |
| Organism | Homo sapiens (Human) |
| Gene Length | 1186 |
| Protein Names | Partner and localizer of BRCA2 |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q86YC2 |
| Gene Card | PALB2 |
| Uniprot ID | Q86YC2 |
| Pfam | PF16756 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.002528(Rat);0.061538(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 2W18 (X-ray 1.90A ) 3EU7 (X-ray 2.20A ) 7S4A (X-ray 2.69A ) |
| DBSNP | rs138789658 rs515726129 rs141047069 rs202194596 rs45594034 rs3809683 rs200620434 rs45494092 rs749461008 rs576081828 rs577969558 rs515726072 rs152451 rs45532440 rs141458731 rs45568339 rs763645981 rs45624036 rs45478192 rs786204248 rs45551636 rs746872839 rs377713277 rs1567206753 rs62625284 rs200283306 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:16793542, ECO:0000269|PubMed:26833090, ECO:0000269|PubMed:28319063}. Note=Colocalizes with BRCA2 and BRCA1 in nuclear foci. {ECO:0000269|PubMed:16793542, ECO:0000269|PubMed:28319063}. |
| Mouse PG classification | NA |
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