| Gene Information | |
|---|---|
| Gene Name | SNAP29 |
| Organism | Homo sapiens (Human) |
| Gene Length | 258 |
| Protein Names | Synaptosomal-associated protein 29 (SNAP-29) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 950 ( ENSG00000099940 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | O95721 |
| Gene Card | SNAP29 |
| Uniprot ID | O95721 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-1.37509167) |
| Ortholog in Animals | Alpaca_ SNAP29 ( ortholog_one2one ) Dog_ SNAP29 ( ortholog_one2one ) GuineaPig_ SNAP29 ( ortholog_one2one ) Mouse_ Snap29 ( ortholog_one2one ) Pig_ SNAP29 ( ortholog_one2one ) Rat_ Snap29 ( ortholog_one2one ) Rabbit_ SNAP29 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | SNAP47, SNAP25, SNAP23 |
| Tissue | NA |
| Tissue Specificity | Found in brain, heart, kidney, liver, lung, placenta, skeletal muscle, spleen and pancreas. {ECO:0000269|PubMed:9852078}. |
| Pharmacological Animal Models | 0.028766(Chimpanzee);0.049857(Mouse);0.002850(Rat);0.039079(Rabbit) |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4WY4 (X-ray 1.40A ) 7BV6 (X-ray 3.05A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm {ECO:0000269|PubMed:23217709}. Golgi apparatus membrane {ECO:0000250|UniProtKB:Q9Z2P6}; Peripheral membrane protein {ECO:0000305}. Cytoplasmic vesicle, autophagosome membrane {ECO:0000269|PubMed:25686604}; Peripheral membrane protein {ECO:0000305}. Cell projection, cilium membrane {ECO:0000269|PubMed:25686250}; Peripheral membrane protein {ECO:0000305}. Note=Appears to be mostly membrane-bound, probably via interaction with syntaxins, but a significant portion is cytoplasmic. Localizes to the ciliary pocket from where the cilium protrudes. {ECO:0000269|PubMed:23217709, ECO:0000269|PubMed:25686250}. |
| Mouse PG classification | LPG |
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