| Gene Information | |
|---|---|
| Gene Name | BRI3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 125 |
| Protein Names | Brain protein I3 (pRGR2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000164713 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | O95415 |
| Gene Card | BRI3 |
| Uniprot ID | O95415 |
| Pfam | PF10164 |
| In ASD | no |
| Allosteric Prediction | no (-1.307253981) |
| Ortholog in Animals | Alpaca_ BRI3 ( ortholog_one2many ) Dog_ BRI3 ( ortholog_one2one ) GuineaPig_ BRI3 ( ortholog_one2one ) Mouse_ Bri3 ( ortholog_one2one ) Pig_ BRI3 ( ortholog_one2one ) Rat_ Bri3 ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs12865 |
| Subcellular location [CC] | Lysosome membrane {ECO:0000305|PubMed:14592447}; Multi-pass membrane protein {ECO:0000255}.; [Isoform 1]: Cytoplasm, perinuclear region {ECO:0000269|PubMed:30983867}. Note=Co-localizes with MGAT1 and IFITM3 at the perinuclear region. {ECO:0000269|PubMed:30983867}.; [Isoform 2]: Cytoplasm {ECO:0000269|PubMed:30983867}. Nucleus {ECO:0000269|PubMed:30983867}. Note=Diffuse localization in the cytoplasm and nucleus. {ECO:0000269|PubMed:30983867}. |
| Mouse PG classification | NA |
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