Gene Information
Gene NamePRKGR2
OrganismHomo sapiens (Human)
Gene Length762
Protein NamescGMP-dependent protein kinase 2 (cGK 2) (cGK2) (EC 2.7.11.12) (cGMP-dependent protein kinase II) (cGKII)
Target NameNA
Target TypeNA
Gene AgeNA
Evolutionary StageNA
AlphaFoldDBQ13237
Gene CardPRKG2
Uniprot IDQ13237
PfamPF00027; PF00069
In ASDno
Allosteric PredictionNA
Ortholog in AnimalsNA
OhnologsNA
ParalogsNA
TissueNA
Tissue SpecificityHighly concentrated in brain, lung and intestinal mucosa.
Pharmacological Animal ModelsNULL(Chimpanzee);NULL(Mouse);0.005990(Rat);NULL(Rabbit)
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB 5BV6  (X-ray  1.94A  5C6C  (X-ray  2.05A  5C8W  (X-ray  1.80A  5JIX  (X-ray  1.47A  5JIZ  (X-ray  1.50A  6BQ8  (Other  2.00A 
DBSNP rs34956759  rs34616910 
Subcellular location [CC]Apical cell membrane {ECO:0000269|PubMed:8636133};
Lipid-anchor {ECO:0000269|PubMed:8636133}.
Mouse PG classificationNA
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