| Gene Information | |
|---|---|
| Gene Name | FAM3B |
| Organism | Homo sapiens (Human) |
| Gene Length | 235 |
| Protein Names | Protein FAM3B (Cytokine-like protein 2-21) (Pancreatic-derived factor) (PANDER) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000183844 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | P58499 |
| Gene Card | FAM3B |
| Uniprot ID | P58499 |
| Pfam | PF15711 |
| In ASD | no |
| Allosteric Prediction | no (-0.898170635) |
| Ortholog in Animals | Alpaca_ FAM3B ( ortholog_one2one ) Dog_ FAM3B ( ortholog_one2one ) Mouse_ Fam3b ( ortholog_one2one ) Pig_ FAM3B ( ortholog_one2one ) Rat_ Fam3b ( ortholog_one2one ) |
| Ohnologs | FAM3A, FAM3D |
| Paralogs | FAM3C, FAM3A, FAM3D |
| Tissue | pancreas, parotid.gland, seminal.vesicle, submandibular.gland, vas.deferens, minor.salivary.gland, small.intestine.Peyers.patch, stomach |
| Tissue Specificity | Highly expressed in the pancreas. Also found in the colon, kidney, prostate, small intestine and testis. {ECO:0000269|PubMed:16114871}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2838012 |
| Subcellular location [CC] | Secreted. Note=Present in insulin secretory granules and likely cosecreted with insulin. Localized in discrete vesicular and perinuclear structure. |
| Mouse PG classification | NA |
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