| Gene Information | |
|---|---|
| Gene Name | FAM35A |
| Organism | Homo sapiens (Human) |
| Gene Length | 835 |
| Protein Names | Shieldin complex subunit 2 (Protein FAM35A) (RINN1-REV7-interacting novel NHEJ regulator 2) (Shield complex subunit 2) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q86V20 |
| Gene Card | SHLD2 |
| Uniprot ID | Q86V20 |
| Pfam | PF15793 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 6KTO (X-ray 3.45A ) 6WWA (X-ray 3.80A ) 7L9P (EM 3.60A ) |
| DBSNP | rs3129520 rs11202365 rs11816168 |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:29656893, ECO:0000269|PubMed:29789392}. Chromosome {ECO:0000269|PubMed:29656893, ECO:0000305|PubMed:29789392}. Note=Localizes to nuclear foci in response to DNA damage. {ECO:0000269|PubMed:29656893, ECO:0000269|PubMed:29789392}. |
| Mouse PG classification | NA |
| click here to return to the previous page | |