| Gene Information | |
|---|---|
| Gene Name | FAM33A |
| Organism | Homo sapiens (Human) |
| Gene Length | 121 |
| Protein Names | Spindle and kinetochore-associated protein 2 (Protein FAM33A) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | NA |
| Evolutionary Stage | NA |
| AlphaFoldDB | Q8WVK7 |
| Gene Card | SKA2 |
| Uniprot ID | Q8WVK7 |
| Pfam | PF16740 |
| In ASD | no |
| Allosteric Prediction | NA |
| Ortholog in Animals | NA |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | NA |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.003490(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 4AJ5 (X-ray 3.32A ) |
| DBSNP | NA |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, spindle {ECO:0000269|PubMed:17093495, ECO:0000269|PubMed:19289083}. Chromosome, centromere, kinetochore {ECO:0000269|PubMed:17093495, ECO:0000269|PubMed:19289083}. Note=Localizes to the outer kinetochore and spindle microtubules during mitosis in a NDC80 complex-dependent manner. Localizes to both the mitotic spindle and kinetochore-associated proteins. {ECO:0000269|PubMed:17093495, ECO:0000269|PubMed:19289083}. |
| Mouse PG classification | NA |
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