| Gene Information | |
|---|---|
| Gene Name | ODF2L |
| Organism | Homo sapiens (Human) |
| Gene Length | 636 |
| Protein Names | Protein BCAP (Basal body centriole-associated protein) (Outer dense fiber protein 2-like) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 987 ( ENSG00000122417 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q9ULJ1 |
| Gene Card | ODF2L |
| Uniprot ID | Q9ULJ1 |
| Pfam | NA |
| In ASD | no |
| Allosteric Prediction | no (-0.937103221) |
| Ortholog in Animals | Alpaca_ ODF2L ( ortholog_one2one ) Dog_ ODF2L ( ortholog_one2one ) GuineaPig_ ODF2L ( ortholog_one2one ) Macaque_ ODF2L ( ortholog_one2one ) Mouse_ Odf2l ( ortholog_one2one ) Pig_ ODF2L ( ortholog_one2one ) Rat_ Odf2l ( ortholog_one2one ) Rabbit_ ODF2L ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | ODF2 |
| Tissue | NA |
| Tissue Specificity | Mainly expressed in trachea and testis. Not detected in bone marrow, bladder, leukocytes. Only weakly detected in tongue, stomach, brain and ovaries. {ECO:0000269|PubMed:17485331}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
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| PDB | NA |
| DBSNP | rs12032435 rs17854440 |
| Subcellular location [CC] | Cytoplasm, cytoskeleton, microtubule organizing center, centrosome {ECO:0000269|PubMed:17485331}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:17485331}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:28775150}. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000269|PubMed:17485331}. Note=Localizes to centrioles in proliferative cells and basal bodies in ciliated cells (PubMed:17485331). Disappears during ciliogenesis but reappears, albeit at a lower levels once ciliogenesis has completed (PubMed:28775150). {ECO:0000269|PubMed:17485331, ECO:0000269|PubMed:28775150}.; [Isoform 1]: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:28775150}. Note=Not present in the centrioles in cycling cells. Disappears during ciliogenesis. {ECO:0000269|PubMed:28775150}.; [Isoform 6]: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriolar satellite {ECO:0000269|PubMed:28775150}. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269|PubMed:28775150}. Note=Disappears during ciliogenesis but reappears, albeit at a lower levels once ciliogenesis has completed. {ECO:0000269|PubMed:28775150}. |
| Mouse PG classification | NA |
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