| Gene Information | |
|---|---|
| Gene Name | DOK3 |
| Organism | Homo sapiens (Human) |
| Gene Length | 496 |
| Protein Names | Docking protein 3 (Downstream of tyrosine kinase 3) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 332 ( ENSG00000146094 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q7L591 |
| Gene Card | DOK3 |
| Uniprot ID | Q7L591 |
| Pfam | PF02174 |
| In ASD | no |
| Allosteric Prediction | no (-1.324143646) |
| Ortholog in Animals | Alpaca_ DOK3 ( ortholog_one2one ) Dog_ DOK3 ( ortholog_one2one ) GuineaPig_ DOK3 ( ortholog_one2one ) Macaque_ DOK3 ( ortholog_one2one ) Mouse_ Dok3 ( ortholog_one2one ) Pig_ DOK3 ( ortholog_one2one ) Rat_ Dok3 ( ortholog_one2one ) Rabbit_ DOK3 ( ortholog_one2one ) |
| Ohnologs | DOK2, DOK1 |
| Paralogs | DOK6, DOK4, DOK2, FRS3, FRS2, DOK1, DOK5 |
| Tissue | spleen, whole.blood |
| Tissue Specificity | Expressed in spleen. {ECO:0000269|PubMed:12595900}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs3749728 rs41275297 |
| Subcellular location [CC] | Cytoplasm {ECO:0000250}. Cell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. |
| Mouse PG classification | NA |
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