| Gene Information | |
|---|---|
| Gene Name | GPA33 |
| Organism | Homo sapiens (Human) |
| Gene Length | 319 |
| Protein Names | Cell surface A33 antigen (Glycoprotein A33) |
| Target Name | cell surface a33 antigen |
| Target Type | Clinical trial target |
| Gene Age | 544 ( ENSG00000143167 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q99795 |
| Gene Card | GPA33 |
| Uniprot ID | Q99795 |
| Pfam | PF07686 |
| In ASD | no |
| Allosteric Prediction | no (-1.089888237) |
| Ortholog in Animals | Alpaca_ GPA33 ( ortholog_one2one ) Dog_ GPA33 ( ortholog_one2one ) GuineaPig_ GPA33 ( ortholog_one2one ) Macaque_ GPA33 ( ortholog_one2one ) Mouse_ Gpa33 ( ortholog_one2one ) Pig_ GPA33 ( ortholog_one2one ) Rat_ Gpa33 ( ortholog_one2one ) Rabbit_ GPA33 ( ortholog_one2one ) |
| Ohnologs | VSIG2, VSIG1, IGSF11, CXADR, CLMP |
| Paralogs | MXRA8, VSIG1, IGSF11, JAM3, VSIG2, JAM2, ESAM, F11R, MUC15, CXADR, VSTM2B, VSIR, VSIG8, CLMP |
| Tissue | colon, duodenum, small.intestine, rectum, transverse.colon |
| Tissue Specificity | Expressed in normal gastrointestinal epithelium and in 95% of colon cancers. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
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| Gene Ontology (cellular component) |
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| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs2274531 rs2228399 |
| Subcellular location [CC] | Membrane; Single-pass type I membrane protein. |
| Mouse PG classification | NA |
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