| Gene Information | |
|---|---|
| Gene Name | FAM20A |
| Organism | Homo sapiens (Human) |
| Gene Length | 541 |
| Protein Names | Pseudokinase FAM20A |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 645 ( ENSG00000108950 ) |
| Evolutionary Stage | Eumetazoa |
| AlphaFoldDB | Q96MK3 |
| Gene Card | FAM20A |
| Uniprot ID | Q96MK3 |
| Pfam | PF06702 |
| In ASD | no |
| Allosteric Prediction | no (-0.404945062) |
| Ortholog in Animals | Alpaca_ FAM20A ( ortholog_one2one ) Dog_ FAM20A ( ortholog_one2one ) GuineaPig_ FAM20A ( ortholog_one2one ) Macaque_ FAM20A ( ortholog_one2one ) Mouse_ Fam20a ( ortholog_one2one ) Pig_ FAM20A ( ortholog_one2one ) Rat_ Fam20a ( ortholog_one2one ) Rabbit_ FAM20A ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | FAM20C, FAM20B |
| Tissue | parotid.gland |
| Tissue Specificity | Highly expressed in lung and liver. Intermediate levels in thymus and ovary. {ECO:0000269|PubMed:15676076}. |
| Pharmacological Animal Models | NULL(Chimpanzee);NULL(Mouse);0.001000(Rat);NULL(Rabbit) |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 5WRR (X-ray 2.51A ) 5WRS (X-ray 2.75A ) 5YH2 (X-ray 3.55A ) 5YH3 (X-ray 3.30A ) |
| DBSNP | rs981673034 rs2302234 rs377432171 rs2907373 |
| Subcellular location [CC] | Secreted {ECO:0000250|UniProtKB:Q8CID3}. Golgi apparatus {ECO:0000269|PubMed:23468644}. Endoplasmic reticulum {ECO:0000250|UniProtKB:Q8CID3}. |
| Mouse PG classification | HPG |
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