| Gene Information | |
|---|---|
| Gene Name | ING5 |
| Organism | Homo sapiens (Human) |
| Gene Length | 240 |
| Protein Names | Inhibitor of growth protein 5 (p28ING5) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 1064 ( ENSG00000168395 ) |
| Evolutionary Stage | Eukaryota |
| AlphaFoldDB | Q8WYH8 |
| Gene Card | ING5 |
| Uniprot ID | Q8WYH8 |
| Pfam | PF12998 |
| In ASD | no |
| Allosteric Prediction | no (-0.977410357) |
| Ortholog in Animals | Alpaca_ ING5 ( ortholog_one2one ) Dog_ ING5 ( ortholog_one2one ) GuineaPig_ ING5 ( ortholog_one2one ) Macaque_ ING5 ( ortholog_one2one ) Mouse_ Ing5 ( ortholog_one2one ) Pig_ ING5 ( ortholog_one2one ) Rat_ Ing5 ( ortholog_one2one ) Rabbit_ ING5 ( ortholog_one2one ) |
| Ohnologs | ING4, ING1 |
| Paralogs | ING3, ING4, ING2, ING1 |
| Tissue | NA |
| Tissue Specificity | Down-regulated in bone marrow cells in acute myeloid leukemia patients as compared with normal bone marrow cells. {ECO:0000269|PubMed:21750715}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | 3C6W (X-ray 1.75A ) 5ME8 (X-ray 3.20A ) 5MTO (X-ray 3.10A ) |
| DBSNP | NA |
| Subcellular location [CC] | Nucleus {ECO:0000269|PubMed:18794358}. Chromosome {ECO:0000269|PubMed:24065767}. Note=Localizes to transcription start sites. {ECO:0000269|PubMed:24065767}. |
| Mouse PG classification | NA |
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