Gene Information
Gene NameOPRPN
OrganismHomo sapiens (Human)
Gene Length248
Protein NamesOpiorphin prepropeptide (Basic proline-rich lacrimal protein) (Proline-rich protein 1) (PRL1) [Cleaved into: Opiorphin]
Target NameNA
Target TypeNA
Gene Age12 ( ENSG00000171199 )
Evolutionary StageMammalia
AlphaFoldDBQ99935
Gene CardOPRPN
Uniprot IDQ99935
PfamPF15621
In ASDno
Allosteric Predictionno (-0.870421904)
Ortholog in AnimalsAlpaca_ OPRPN ( ortholog_one2one )
Macaque_ OPRPN ( ortholog_one2one )
OhnologsNA
ParalogsNA
Tissuesalivary.gland, breast
Tissue SpecificityAbundantly expressed in lacrimal gland where it found in the secretory endpieces. Also expressed at modest levels in the submandibular gland.
Pharmacological Animal ModelsNA
Gene Ontology
(biological process)
Gene Ontology
(cellular component)
Gene Ontology
(molecular function)
PDB NA 
DBSNP NA 
Subcellular location [CC]Secreted {ECO:0000269|PubMed:17101991}.
Mouse PG classificationNA
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