| Gene Information | |
|---|---|
| Gene Name | MPLKIP |
| Organism | Homo sapiens (Human) |
| Gene Length | 179 |
| Protein Names | M-phase-specific PLK1-interacting protein (TTD non-photosensitive 1 protein) |
| Target Name | NA |
| Target Type | NA |
| Gene Age | 70 ( ENSG00000168303 ) |
| Evolutionary Stage | Vertebrata |
| AlphaFoldDB | Q8TAP9 |
| Gene Card | MPLKIP |
| Uniprot ID | Q8TAP9 |
| Pfam | PF15502 |
| In ASD | no |
| Allosteric Prediction | no (-1.635527103) |
| Ortholog in Animals | Alpaca_ MPLKIP ( ortholog_one2one ) Dog_ MPLKIP ( ortholog_one2one ) GuineaPig_ MPLKIP ( ortholog_one2one ) Macaque_ MPLKIP ( ortholog_one2one ) Mouse_ Mplkip ( ortholog_one2many ) Mouse_ Gm7102 ( ortholog_one2many ) Pig_ MPLKIP ( ortholog_one2one ) Rat_ Mplkip ( ortholog_one2one ) Rabbit_ MPLKIP ( ortholog_one2one ) |
| Ohnologs | NA |
| Paralogs | NA |
| Tissue | NA |
| Tissue Specificity | Expressed at highest levels in liver and kidney; intermediate expression in skeletal muscle, pancreas, heart and placenta; low expression in brain and lung. Expressed in epidermis and hair follicles. {ECO:0000269|PubMed:11829489, ECO:0000269|PubMed:15645389}. |
| Pharmacological Animal Models | NA |
| Gene Ontology (biological process) |
|
| Gene Ontology (cellular component) |
|
| Gene Ontology (molecular function) |
|
| PDB | NA |
| DBSNP | rs565833937 rs137853117 |
| Subcellular location [CC] | Nucleus. Cytoplasm. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Note=The subcellular location is regulated during cell cycle. During interphase located in the nucleus. During mitosis located at the centrosome and dispersed in the cytoplasm. During telophase located in the midbody. Colocalizes with PLK1 at the centrosome in M phase. |
| Mouse PG classification | NA |
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